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Throughout 2019, the TSC Alliance will celebrate our sapphire, 45th anniversary. This milestone is only possible due to the tenacity of untold numbers of tuberous sclerosis complex (TSC) community members, physicians, researchers, staff and board members, partner organizations and other supporters who help us work toward our mission to find a cure for TSC while improving the lives of those affected.

As we reflect on our history, we will celebrate the accomplishments that make up our blue brick road. In this issue we look back to the 2000s and the first FDA-approved treatment for TSC and expansion of research and fundraising initiatives.